James Marsden

as Diggs (voice)

Born 09/18/1973, age

Nick Nolte

as Butch (voice)

Born 02/08/1941, age

Christina Applegate

as Catherine (voice)

Born 11/25/1971, age

Bette Midler

as Kitty Galore (voice)

Born 12/01/1945, age

Pascale Hutton

as Jackie

Born 06/14/1979, age

Katt Williams

as Seamus (voice)

Born 09/02/1973, age

Neil Patrick Harris

as Lou (voice)

Born 06/15/1973, age

Sean Hayes

as Mr. Tinkles (voice)

Born 06/26/1970, age

Wallace Shawn

as Calico (voice)

Born 11/12/1943, age

Roger Moore

as Tab Lazenby (voice)

Born 10/14/1927

Died 05/23/2017, age

Joe Pantoliano

as Peek (voice)

Born 09/12/1951, age

Michael Clarke Duncan

as Sam (voice)

Born 12/10/1957

Died 09/03/2012, age

Chris O'Donnell

as Shane

Born 06/26/1970, age

Jack McBrayer

as Chuck

Born 05/27/1973, age

Fred Armisen

as Freidrich

Born 12/04/1966, age

Kiernan Shipka

as Little Girl

Born 11/10/1999, age

Paul Rodríguez

as Crazy Carlito (voice)

Born 01/19/1955, age

J.K. Simmons

as Gruff K-9 (voice)

Born 01/09/1955, age

Grey DeLisle

as Security Bulldog/Catherine's Niece/Cat Spy Analyst

Born 08/24/1973, age

Elizabeth Daily

as Scrumptious / Patches / Catherine's Niece (voice)

Born 09/11/1961, age

Phil LaMarr

as Paws / Cat Spy Analyst (voice)

Born 01/24/1967, age

Jeff Bennett

as Duncan MacDougall (voice)

Born 10/02/1962, age

Keith Dallas

as Coit Tower Guard

Born 05/10/1978, age

Bumper Robinson

as Cool Cat / Dog Killa / Cat Spy Analyst / Slim (voice)

Born 06/19/1974, age

Rick D. Wasserman

as Rocky (voice)

Born 10/17/1973, age

Roger L. Jackson

as Inmate Fat Cat (voice)

Born 07/13/1958, age

Carlos Alazraqui

as Cat Gunner / Cat Spy Analyst (voice)

Born 07/20/1962, age

Grey DeLisle

as Security Bulldog / Catherine's Niece / Cat Spy Analyst (voice)

Born 08/24/1973, age